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Valeria Cento

Associate Professor

Microbiology and Clinical Microbiology

Associate Professor; President of BSc in Biomedical Laboratory Techniques; Director of the Postgraduate Residency Program for Microbiology and Virology

E-mail

valeria.cento@hunimed.eu
Sito

www.hunimed.eu/faculty/

Education

2011-2017 Medicine and Surgery Degree, University of Rome “Tor Vergata”, Rome, Italy
2008-2011 PhD in Medical Microbiology and Immunology, University of Rome “Tor Vergata”, Rome, Italy
2006-2008 Second level degree in Medical Biotechnologies, University of Rome “Tor Vergata”, Rome, Italy
2003-2006 First level degree in Biotechnologies, Universita’ degli Studi di SIENA, Siena, Italy

Teaching appointments

MEDTEC School – Microbiology module in the Pathology, Immunology and Microbiology integrated course
Medicine and Surgery – Clinical Microbiology module in the Mechanisms of diseases II and in the Infectious Diseases and Clinical Microbiology integrated courses
Nursing – Microbiologia e Microbiologia Clinica module in the Promozione della salute e della sicurezza nella comunità integrated course
Physioterapy –Microbiologia module in the Scienze Biologiche integrated course
Medical Laboratory Techinicians – Microbiologia Generale module in the Immunologia, Patologia e Microbiologia integrated course
Teacher in the Schools of Specialization in Internal Medicine, and Hygiene and Preventive Medicine

Academic background

2020-2021 Assistant professor at Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milano, Italy
2012-2018 Post-doc fellow at Department of Experimental Medicine and Surgery, University of Rome “Tor Vergata”, Rome, Italy

Present academic appointment

Associate professor in Microbiology and Clinical Microbiology

Other institutional appointments

President of the Degree in “Tecniche di Laboratorio Biomedico” – Humanitas University

Scientific Responsible of Microbiology Laboratory – IRCCS Humanitas Research Hospital

Affiliations (for those who also have an external affiliation)

Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele – Milan, Italy
IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano – Milan, Italy

Academic honors, awards and prices

2011 Award for the best oral communication at the “3rd Italian Congress on AIDS and Retrovirus”, Florence (Italy) (co-author, Santoro et al.)
2016 Award for the best “Poster of Basic Sciences” at the 49th A.I.S.F. – Italian Association for the Study of the Liver, Rome (Italy) (co-author Sorbo M.C. et al.)
2017 Award for the best oral communication in Clinical Hepatitis at the IX ICAR National Congress, Siena (Italy)
2017 First prize in the “Clinical Studies” session in the Under 40 Infection Lab project, Bologna (Italy)
2017, 2018 Scientific Secretariat of the 10th and 11th National ICAR Congresses (Italian Conference on AIDS and Antiviral Research), Rome (Italy)
2018, 2019 Scientific jury of the Under 40 Infection Lab 2018 and 2019 projects
Reviewer for numerous national and international scientific journals

Main research interest in clinical translational projects, centered on genetic characterization of human viruses and definition of mechanisms of drug-resistance development and immune escape in chronic and acute viral infections. Detailed characterization of viral genetic features also relied on phylogenetic studies and assessment of pathways of viral transmission in community and nosocomial settings.

Latest research interests include the management of complicated infections in fragile and hospitalized patients, including those sustained by fungi and multi-drug resistant bacteria. During her working activity, she also focused on the optimization of diagnostic protocols used in clinical microbiology for fragile patients, especially those for reactivating viral infection in transplant settings.

Pani, A., Cento, V., Vismara, C., Campisi, D., Di Ruscio, F., Romandini, A., Senatore, M., Schenardi, P.A., Gagliardi, O.M., Giroldi, S., Zoppini, L., Moreno, M., Corradin, M., Epis, O.M., Ughi, N., Cuppari, I., Crocchiolo, R., Merli, M., Bosio, M., Rossini, S., Puoti, M., Scaglione, F. Results of the RENAISSANCE Study: REsponse to BNT162b2 COVID-19 vacciNe—short- And long-term Immune reSponSe evAluatioN in health Care workErs. (2021) Mayo Clinic Proceedings, 96 (12), pp. 2966-2979.
Alteri C*, Cento V*, Piralla A*, Costabile V, Tallarita M, Colagrossi L, Renica S, Giardina F, Novazzi F, Gaiarsa S, Matarazzo E, Antonello M, Vismara C, Fumagalli R, Epis OM, Puoti M, Perno CF, Baldanti F. Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy. Nat Commun. 2021 Jan 19;12(1):434. *Equal contribution
Cento V, Colagrossi L, Nava A, Lamberti A, Senatore S, Travi G, Rossotti R, Vecchi M, Casati O, Matarazzo E, Bielli A, Casalicchio G, Antonello M, Renica S, Costabile V, Scaglione F, Fumagalli R, Ughi N, Epis OM, Puoti M, Vismara C, Faccini M, Fanti D, Alteri C, Perno CF. Persistent positivity and fluctuations of SARS-CoV-2 RNA in clinically-recovered COVID-19 patients. J Infect. 2020.
Cento, V., Alteri, C., Mancini, V., Gatti, M., Lepera, V., Mazza, E., Moioli, M.C., Merli, M., Colombo, J., Orcese, C.A., Bielli, A., Torri, S., Gasparini, L.E., Vismara, C., De Gasperi, A., Brioschi, P., Puoti, M., Cairoli, R., Lombardi, G., Perno, C.F. Quantification of 1,3-β-d-glucan by Wako β-glucan assay for rapid exclusion of invasive fungal infections in critical patients: A diagnostic test accuracy study (2020) Mycoses, 63 (12).
Cento V, Mirabelli C, Salpini R, Dimonte S, Artese A, Costa G, Mercurio F, Svicher V, Parrotta L, Bertoli A, Ciotti M, Di Paolo D, Sarrecchia C, Andreoni M, Alcaro S, Angelico M, Perno CF, Ceccherini-Silberstein F. HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors. PLoS One. 2012;7(7):e39652.